Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/31783
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: The nutritional and cardiovascular health benefits of rapeseed oil-fed farmed salmon in humans are not decreased compared with those of traditionally farmed salmon: a randomized controlled trial
Author(s): de Roos, Baukje
Wood, Sharon
Bremner, David
Bashir, Shabina
Betancor, Monica B
Fraser, William D
Duthie, Susan J
Horgan, Graham W
Sneddon, Alan A
Keywords: Farmed fish
Fish feeds
Cardiovascular health
Omega-3 index
Vitamin D
Micronutrients
Issue Date: Jun-2021
Date Deposited: 8-Oct-2020
Citation: de Roos B, Wood S, Bremner D, Bashir S, Betancor MB, Fraser WD, Duthie SJ, Horgan GW & Sneddon AA (2021) The nutritional and cardiovascular health benefits of rapeseed oil-fed farmed salmon in humans are not decreased compared with those of traditionally farmed salmon: a randomized controlled trial. European Journal of Nutrition, 60 (4), pp. 2063-2075. https://doi.org/10.1007/s00394-020-02396-w
Abstract: Purpose Farmed fish are increasingly raised on feeds containing vegetable oils, which affects their composition and possibly health properties. We investigated the effects of consuming farmed salmon, raised on different feeding regimes, on nutrient status and health outcomes in healthy subjects. Methods Salmon were grown on feeds containing mainly fish oil (FO) or rapeseed oil (RO), resulting in an eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA) content of fillets of 2.1 or 0.9 g/100 g, respectively. In a randomized parallel controlled trial, 51 healthy subjects were allocated to consume 2 portions/week of FO salmon (n = 17), RO salmon (n = 17) or no additional salmon (Control, n = 17) as part of their habitual diet, for 18 weeks. We collected blood at 0, 9 and 18 weeks to measure omega-3 index (O3I) in red blood cells, plasma markers of cardiovascular risk, serum 25(OH)-vitamin D3 (25(OH)D3) and plasma trace elements. Results: After 18 weeks, O3I was similarly increased in subjects consuming 2 portions/week of FO or RO salmon compared to control (both p < 0.05). Serum 25(OH)D3 was significantly higher, whereas plasma triacylglycerols were significantly lower in subjects consuming RO salmon compared to control (both p < 0.05). Heart rate was significantly lower in subjects consuming FO salmon after 9 weeks, compared to control (p < 0.01). Salmon consumption did not affect other markers. Conclusion: Consuming two portions/week of salmon raised on rapeseed oil rather than fish oil increased the O3I and vitamin D status, and decreased plasma triacylglycerols. These outcomes endorse opportunities for developing more sustainable feeds within aquaculture food systems. Clinical trial registry: This trial was registered at clinicaltrials.gov as NCT01916434.
DOI Link: 10.1007/s00394-020-02396-w
Rights: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Licence URL(s): http://creativecommons.org/licenses/by/4.0/

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