STORRE
STORRE: Stirling Online Research Repository
Please use this identifier to cite or link to this item:
http://hdl.handle.net/1893/38344| Appears in Collections: | Biological and Environmental Sciences Journal Articles |
| Peer Review Status: | Refereed |
| Title: | One Health insights into local transmission of zoonotic Schistosoma mattheei in southern Malawi |
| Author(s): | Juhász, Alexandra Makaula, Peter Cunningham, Lucas J Nkolokosa, Clinton Archer, John Jones, Sam Namacha, Gladys Chammudzi, Priscilla Mainga, Bright Lally, David Kayuni, Sekeleghe A LaCourse, E James O'Ferrall, Angus M Musaya, Janelisa Stothard, J Russell |
| Contact Email: | clinton.nkolokosa@stir.ac.uk |
| Keywords: | schistosomiasis microepidemiology DNA barcoding hybridization livestock normalized difference vegetation index |
| Issue Date: | 8-Jan-2026 |
| Date Deposited: | 10-Sep-2026 |
| Citation: | Juhász A, Makaula P, Cunningham LJ, Nkolokosa C, Archer J, Jones S, Namacha G, Chammudzi P, Mainga B, Lally D, Kayuni SA, LaCourse EJ, O'Ferrall AM, Musaya J & Stothard JR (2026) One Health insights into local transmission of zoonotic Schistosoma mattheei in southern Malawi. <i>Philosophical Transactions B</i>, 381 (1941). https://doi.org/10.1098/rstb.2024.0519 |
| Abstract: | Schistosoma mattheei is a zoonotic schistosome species in central and southern Africa and is of increasing public health concern in southern Malawi. To gain insight into its local transmission, we investigated the biology of Schistosoma mattheei in southern Malawi, integrating epidemiological, environmental and genetic data within a One Health framework. Cattle, goats, humans and snails were surveyed, with DNA barcoding revealing nine mitochondrial S. mattheei haplotypes. Two haplotypes were shared across species, indicating cross-host transmission. Infected snails were detected year-round, with seasonal variation linked to vegetation cover (Normalized Difference Vegetation Index (NDVI)). Praziquantel (40 mg kg−1) treatment in selected cattle herds reduced infection prevalence over 12 weeks. These findings highlight the zoonotic potential of S. mattheei and the need for integrated control strategies. |
| DOI Link: | 10.1098/rstb.2024.0519 |
| Rights: | Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited |
| Licence URL(s): | http://creativecommons.org/licenses/by/4.0/ |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| rstb.2024.0519.pdf | Fulltext - Published Version | 1.59 MB | Adobe PDF | View/Open |
This item is protected by original copyright |
A file in this item is licensed under a Creative Commons License
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved https://creativecommons.org/publicdomain/zero/1.0/
If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.